Pathway-based personalized analysis of cancer
نویسندگان
چکیده
منابع مشابه
Pathway-based personalized analysis of cancer.
We introduce Pathifier, an algorithm that infers pathway deregulation scores for each tumor sample on the basis of expression data. This score is determined, in a context-specific manner, for every particular dataset and type of cancer that is being investigated. The algorithm transforms gene-level information into pathway-level information, generating a compact and biologically relevant repres...
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تعارفات کنش های گفتاری هستند که افراد در زندگی روزمر? خود به منظور برقراری دوستی یا تداوم روابط مسالمت آمیز به کار می برند. ساز و کار تعارف مختص زبان انگلیسی یا هر زبان دیگری نیست و پدیده ای است جهانی و در همه زبانها حضور دارد. تفاوتی که از این نظر در زبانها و فرهنگ ها وجود دارد مربوط به پاسخ به این کنش گفتاری در گفتمان است. این مطالعه به بررسی تنوع پاسخ های انگلیسی و عربی به کنش گفتاری تعارف د...
Identification of Personalized Chemoresistance Genes in Subtypes of Basal-Like Breast Cancer Based on Functional Differences Using Pathway Analysis
Breast cancer is a highly heterogeneous disease that is clinically classified into several subtypes. Among these subtypes, basal-like breast cancer largely overlaps with triple-negative breast cancer (TNBC), and these two groups are generally studied together as a single entity. Differences in the molecular makeup of breast cancers can result in different treatment strategies and prognoses for ...
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BACKGROUND Breast cancer is a heterogeneous disease that encompasses a wide range of clinical behaviors and histological and molecular variants. It is the most common type of cancer affecting women worldwide and is the second leading cause of cancer death. METHODS A comprehensive literature search was performed to explore the advances in molecular medicine related to the diagnosis and treatme...
متن کاملPersonalized analysis of pathway aberrance induced by sevoflurane and propofol
Anesthetic agents are used in surgical operations to reversibly reduce consciousness and pain. Sevoflurane is an inhalational anesthetic. Propofol is a short‑acting intravenous general anesthetic. The mechanism of anesthetic agents at pathway level on individual patients has not been reported to date. In the present study, pathway aberrance in the human atrial tissue in response to anesthetics ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2013
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1219651110